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Novel Receptor Targets and Mechanisms
Poster sessions - all posters to be displayed throughout

P001 Phosphorylation of Juxtamembrane C-terminal of  CB1 Cannabinoid Receptor in NT18TG2 Cells
Khalil Eldeeb*1, Sudha M. Cowsik2, Allyn C. Howlett1
1Wake Forest University, USA, 2Jawaharlal Nehru University, India
P003 Chromenopyrazole as Versatile Cannabinoid Scaffold: from CB1 towards CB2 Selectivity
Paula Morales*1, Maria Gómez-Cañas2, Dow P. Hurst3, Moisés Garcia-Arencibia2, Javier Fernández-Ruiz2, Patricia Reggio3, Pilar Goya1, Nadine Jagerovic1
1Consejo Superior de Investigaciones Científicas, Instituto de Química Médica, Spain, 2Facultad de Medicina, Universidad Complutense de Madrid, Departamento de Bioquímica y Biología Molecular. Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Ins, Spain, 3Department of Chemistry and Biochemistry, University of North Carolina Greensboro, USA
P004 The 11-hydroxy Metabolite Of Δ9-Tetrahydrocannabivarin Behaves As An Apparent CB1 and CB2 Receptor Neutral Antagonist
Maria Grazia Cascio*, Pietro Marini, Daniele Bolognini, Roger G. Pertwee
University of Aberdeen, UK
P005 Cannabinoid Receptors in Human and Rat (Wistar and Zucker) Skeletal Muscle
Fairouz Shermado*, kostas Tsintzas, Bennett Andrew
University of Nottingham, UK
P006 Rimonabant Multiple Ligands Targeting CB and PPAR Receptors
Nieves Fresno*1, Ruth Pérez-Fernández1, Manuel Macías-González2,3, José Elguero1, Juan Decara3,4, María Gómez-Cañas5, Moisés García-Arencibia5, Javier Fernandez-Ruiz5, Fernando Rodríguez de Fonseca3,4, Pilar Goya1
1Instituto de Química Médica, IQM-CSIC, Spain, 2Servicio de Endocrinología Nutrición, Hospital Virgen de la Victoria (Fundación IMABIS), CIBER Fisiopatología de la Obesidad y Nutrición. CB06/03, Instituto de Salud Carlos III, Spain, 3Fundación Hospital Carlos Haya, Spain, 4CIBER OBN (Centro de Investigación Biomédica en Red de la Fisiopatología de la Obesidad y Nutrición), Instituto de Salud Carlos III, Ministerio de Ciencia e Innovación, Spain, 5Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad Complutense de Madrid; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED); Ins, Spain
P007 The Pharmacological Effects Of Palmitoylethanolamide (PEA) On Intestinal Permeability In Vitro Using Caco-2 Cell
Mustafa Karwad*, Jonathan Lund, Mike Larvin, Saoirse O'Sullivan
University of Nottingham, UK
P008 Pyrazole-Type Cannabinoid Ligands Conjugated With Fluoro-deoxy-carbohydrates As Potential PET-Imaging Agents: Synthesis And CB1/CB2 Receptor Affinity Evaluation
Simona Frau*1, Sergio Dall'Angelo1, Gemma L. Baillie1, Ruth A. Ross1, Marilena Pira2, Paolo Lazzari2, Matteo Zanda1
1Kosterlitz Centre for Therapeutics, Institute of Medical Sciences, University of Aberdeen, UK, 2Neuroscienze PharmaNess Scarl, Parco Scientifico della Sardegna, Italy
P009 Pepcan localization and potential role in the rodent central nervous system
Stefanie Hofer*1, William Ralvenius2, Hanns Ulrich Zeilhofer2, Jürg Gertsch1
1Institue of Biochemistry and Molecular Medicine, University of Bern, Switzerland, 2Institute of Pharmacology and Toxicology, University of Zürich, Switzerland
P010 WOBE437 - Prototype of a novel class of potent, selective endocannabinoid reuptake inhibitors
Simon Nicolussi*1, Andrea Chicca1, Michael Soeberdt2, Christoph Abels2, Juan Manuel Viveros Paredes3, Alejandro Aparisi Rey4, Beat Lutz4, Jürg Gertsch1
1Institute of Biochemistry and Molecular Medicine, University of Berne, Switzerland, 2Dr.August Wolff Arzneimitte, Germany, 3Institute of Immunopharmacology, University of Guadalajara, Mexico, 4Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Germany
P011 5-HT1A Receptors Mediate the Motor Effects of the Non-Psychotropic Phytocannabinoid Cannabidiol
Francisco Espejo-Porras*1, Javier Fernández-Ruiz1, Roger G. Pertwee2, Raphael Mechoulam3, Concepción García1
1Department of Biochemistry and Molecular Biology, Faculty of Medicine, Complutense University, and CIBERNED and IRYCIS, Spain, 2School of Medical Sciences, Institute of Medical Sciences, University of Aberdeen, UK, 3Department od Medicinal Chemistry and Natural Products, Medical Faculty, Hebrew University, Israel
P012 A hydrolysis-resistant fluorescent endocannabinoid analogue to investigate cellular endocannabinoid uptake and trafficking
Andrea Chicca*1, Simon Nicolussi1, Silvia Ortega Gutierrez2, Jürg Gertsch1
1Institute of Biochemistry and Molecular Medicine, University of Bern, Switzerland, 2Universidad Computense Madrid, Spain
P013 Human osteoblast (HOB) proliferation and differentiation in vitro is affected by a range of novel endocannabinoids.
Kate Hadley-Brown, Susan Anderson*, Marie Smith, Saoirse O'Sullivan
University of Nottingham, UK
P014 Study of Trpv1, Trpv2 and Trpa1 channels activation by cannabidiol (CBD) and cannabivarine (CBDV) in whole-cell patch clamp analysis
Fabio Arturo Iannotti*1, Camille Soubrane2, Vincenzo Di Marzo1, Gary Stephens0
1National Council of Research (CNR), Institute of Biomecular Chemestry (ICB), Italy, 2School of Pharmacy, University of Reading, UK
P015 Pharmacological Characterisation Of A Binding Site For Leelamine
William Devane*, David Finn
National University of Ireland, Galway, Ireland
P016 Role of the Transient Receptor Potential Vanilloid-type2 Agonist Cannabidiol in Multiple Mieloma
Maria Beatrice Morelli1, Massimo Offidani3, Giancarlo Discepoli4, Matteo Santoni5, Consuelo Amantini1, Valerio Farfariello0,6, Sonia Liberati2, Pietro Leoni3, Giorgio Santoni1, Massimo Nabissi*1
1School of Pharmacy, Section of Experimental Medicine, University of Camerino, Italy, 2Dept Molecular Medicine, Sapienza University, Italy, 3Clinic of Haematology, Azienda Ospedaliero-Universitaria Ospedali Riuniti Ancona, Italy, 4Centre of Genetic Medicine and Prenatal Diagnosis, Az.Osp, G.Salesi, Italy, 5Dept of Clinic Oncology, Polytechnic University of Marche, Italy, 6Dept of Urology and Andrology, University of Perugia, Italy
P017 The endocannabinoid-like mediator DHEA (docosahexaenoylethanolamide) modulates COX-2 activity
JOCELIJN MEIJERINK*, MIEKE POLAND, MICHIEL BALVERS, RENGER WITKAMP
HUMAN NUTRITION/NUTRITION AND PHARMACOLOGY, The Netherlands
P018 PLASMA MEMBRANE AND INTRACELLULAR CB1 RECEPTORS MODULATE PROLIFERATION AND MIGRATION OF OLIGODENDROCYTE PROGENITOR CELLS
M Alejandra Sanchez-Rodriguez1, Oscar Gomez1, MQ Uyen Le1, Concepcion Sanchez-Caro1, Francisco Molina-Holgado2, Eduardo Molina-Holgado*1
1Laboratorio de Neuroinflamacion, Hospital Nacional de Paraplejicos, Spain, 2Department of Life Sciences, Health Sciences Research Centre, University of Roehampton, UK